Unique gene expression and MR T2 relaxometry patterns define chronic murine dextran sodium sulphate colitis as a model for connective tissue changes in human Crohn's disease.

Unique gene expression and MR T2 relaxometry patterns define chronic murine dextran sodium sulphate colitis as a model for connective tissue changes in human Crohn's disease.

INTRODUCTION: Chronically relapsing inflammation, tissue remodeling and fibrosis are hallmarks of inflammatory bowel diseases. The aim of this study was to investigate changes in connective tissue in a chronic murine model resulting from repeated cycles of dextran sodium sulphate (DSS) ingestion, to...

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Bibliographic Details
Main Authors: Christine Breynaert, Tom Dresselaers, Clémentine Perrier, Ingrid Arijs, Jonathan Cremer, Leentje Van Lommel, Kristel Van Steen, Marc Ferrante, Frans Schuit, Séverine Vermeire, Paul Rutgeerts, Uwe Himmelreich, Jan L Ceuppens, Karel Geboes, Gert Van Assche
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3720888?pdf=render

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http://europepmc.org/articles/PMC3720888?pdf=render

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