In Silico and In Vitro Experimental Studies of New Dibenz[<i>b</i>,<i>e</i>]oxepin-11(6<i>H</i>)one O-(arylcarbamoyl)-oximes Designed as Potential Antimicrobial Agents

In Silico and In Vitro Experimental Studies of New Dibenz[<i>b</i>,<i>e</i>]oxepin-11(6<i>H</i>)one O-(arylcarbamoyl)-oximes Designed as Potential Antimicrobial Agents

In a drug-repurposing-driven approach for speeding up the development of novel antimicrobial agents, this paper presents for the first time in the scientific literature the synthesis, physico-chemical characterization, in silico analysis, antimicrobial activity against bacterial and fungal strains i...

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Bibliographic Details
Main Authors: Ilinca Margareta Vlad, Diana Camelia Nuta, Cornel Chirita, Miron Teodor Caproiu, Constantin Draghici, Florea Dumitrascu, Coralia Bleotu, Speranța Avram, Ana Maria Udrea, Alexandru Vasile Missir, Luminita Gabriela Marutescu, Carmen Limban
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Molecules
Subjects:
dibenz[<i>b</i>,<i>e</i>]oxepins
oxime carbamates
antibacterial
antifungal
antibiofilm
in silico
in vitro cytotoxicity
Online Access:https://www.mdpi.com/1420-3049/25/2/321

Internet

https://www.mdpi.com/1420-3049/25/2/321

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