Development of a Simple and Robust Whole Blood Assay with Dual Co-Stimulation to Quantify the Release of T-Cellular Signature Cytokines in Response to <i>Aspergillus fumigatus</i> Antigens

Development of a Simple and Robust Whole Blood Assay with Dual Co-Stimulation to Quantify the Release of T-Cellular Signature Cytokines in Response to <i>Aspergillus fumigatus</i> Antigens

Deeper understanding of mold-induced cytokine signatures could promote advances in the diagnosis and treatment of invasive mycoses and mold-associated hypersensitivity syndromes. Currently, most T-cellular immunoassays in medical mycology require the isolation of mononuclear cells and have limited r...

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Bibliographic Details
Main Authors: Chris D. Lauruschkat, Lukas Page, P. Lewis White, Sonja Etter, Helen E. Davies, Jamie Duckers, Frank Ebel, Elisabeth Schnack, Matthijs Backx, Mariola Dragan, Nicolas Schlegel, Olaf Kniemeyer, Axel A. Brakhage, Hermann Einsele, Juergen Loeffler, Sebastian Wurster
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Journal of Fungi
Subjects:
immunoassay
biomarker
<i>Aspergillus</i>
cytokines
inflammation
adaptive immunity
Online Access:https://www.mdpi.com/2309-608X/7/6/462

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https://www.mdpi.com/2309-608X/7/6/462

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