Geometrically controlled asymmetric division of CD4+ T cells studied by immunological synapse arrays.

Similar to stem cells, naïve T cells undergo asymmetric division following activation. While asymmetric division of T cells has been shown to be an important mechanism for the generation of lymphocyte fate diversity during immune responses, key factors that influence whether T cells will undergo sym...

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Bibliographic Details
Main Authors: Hong-Ryul Jung, Kwang Hoon Song, John T Chang, Junsang Doh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3954838?pdf=render