Whole exome sequencing of an asbestos-induced wild-type murine model of malignant mesothelioma

Whole exome sequencing of an asbestos-induced wild-type murine model of malignant mesothelioma

Abstract Background Malignant mesothelioma (MM) is an aggressive cancer of the pleural and peritoneal cavities caused by exposure to asbestos. Asbestos-induced mesotheliomas in wild-type mice have been used extensively as a preclinical model because they are phenotypically identical to their human c...

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Bibliographic Details
Main Authors: Sophie Sneddon, Ann-Marie Patch, Ian M. Dick, Stephen Kazakoff, John V. Pearson, Nicola Waddell, Richard J. N. Allcock, Robert A. Holt, Bruce W. S. Robinson, Jenette Creaney
Format: Article
Language:English
Published: BMC 2017-06-01
Series:BMC Cancer
Subjects:
Mesothelioma
Asbestos
Exome sequencing
Cdkn2a
Mouse model
Wild-type
Online Access:http://link.springer.com/article/10.1186/s12885-017-3382-6

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http://link.springer.com/article/10.1186/s12885-017-3382-6

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