Retinal angiotensin II and angiotensin-(1-7) response to hyperglycemia and an intervention with captopril

Hypothesis: Hyperglycemia decreases angiotensin-(1-7), the endogenous counter-regulator of angiotensin II in the retina. Materials and methods: The distribution and levels of retinal angiotensin II (Ang II) and angiotensin-(1-7) (Ang-(1-7)) were evaluated by confocal imaging and quantitative immunoh...

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Bibliographic Details
Main Authors: Preenie deS Senanayake, Vera L Bonilha, John W Peterson, Yoshiro Yamada, Sadashiva S Karnik, Firouz Daneshgari, K Bridget Brosnihan, Joe G Hollyfield
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2018-08-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320318789323