Case Report: Identification of Potential Prognosis-Related TP53 Mutation and BCL6-LPP Fusion in Primary Pituitary Lymphoma by Next Generation Sequencing: Two Cases

Case Report: Identification of Potential Prognosis-Related TP53 Mutation and BCL6-LPP Fusion in Primary Pituitary Lymphoma by Next Generation Sequencing: Two Cases

BackgroundPrimary pituitary lymphoma (PPL) is an extremely rare disease with poor prognosis. Although PPL has been shown to be different from classical primary central nervous system lymphoma because of the embryological origin of structures, individual and precise treatment of PPL remains unknown.M...

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Bibliographic Details
Main Authors: Yi Zhang, Liyuan Ma, Jie Liu, Huijuan Zhu, Lin Lu, Kan Deng, Wenbin Ma, Hui Pan, Renzhi Wang, Yong Yao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Endocrinology
Subjects:
primary pituitary lymphoma
TP53
BCL6
high-dose methotrexate
diffuse large B cell lymphoma
next generating sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.673908/full

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https://www.frontiersin.org/articles/10.3389/fendo.2021.673908/full

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