Overexpression of the mitochondrial T3 receptor induces skeletal muscle atrophy during aging.

Overexpression of the mitochondrial T3 receptor induces skeletal muscle atrophy during aging.

In previous studies, we characterized a new hormonal pathway involving a mitochondrial T3 receptor (p43) acting as a mitochondrial transcription factor. In in vitro and in vivo studies, we have shown that p43 increases mitochondrial transcription and mitochondrial biogenesis. In addition, p43 overex...

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Bibliographic Details
Main Authors: François Casas, Laurence Pessemesse, Stéphanie Grandemange, Pascal Seyer, Olivier Baris, Naïg Gueguen, Christelle Ramonatxo, Florence Perrin, Gilles Fouret, Laurence Lepourry, Gérard Cabello, Chantal Wrutniak-Cabello
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2680484?pdf=render

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http://europepmc.org/articles/PMC2680484?pdf=render

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