Pharmacogenetics of advanced lung cancer: Predictive value of functional genetic polymorphism AGXT Pro11Leu in clinical outcome?

Introduction: AGXT gene codes for the enzyme alanine glyoxylate aminotransferase, which is involved in hepatic peroxisomal metabolism of platinum-based chemotherapeutic agents. The association of genetic variant AGXT rs34116584 on the clinical outcome and response to chemotherapy of patients with no...

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Bibliographic Details
Main Authors: Maria Joana Catarata, Margarida Lourenço, Maria Fátima Martins, João Frade, Alice Pêgo, Carlos Robalo Cordeiro, Rui Medeiros, Ricardo Ribeiro
Format: Article
Language:English
Published: Elsevier España 2021-03-01
Series:Pulmonology
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Online Access:http://www.sciencedirect.com/science/article/pii/S2531043720302506