Pharmacogenetics of advanced lung cancer: Predictive value of functional genetic polymorphism AGXT Pro11Leu in clinical outcome?
Introduction: AGXT gene codes for the enzyme alanine glyoxylate aminotransferase, which is involved in hepatic peroxisomal metabolism of platinum-based chemotherapeutic agents. The association of genetic variant AGXT rs34116584 on the clinical outcome and response to chemotherapy of patients with no...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier España
2021-03-01
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Series: | Pulmonology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2531043720302506 |