Tristetraprolin mediates radiation-induced TNF-α production in lung macrophages.

Tristetraprolin mediates radiation-induced TNF-α production in lung macrophages.

The efficacy of radiation therapy for lung cancer is limited by radiation-induced lung toxicity (RILT). Although tumor necrosis factor-alpha (TNF-α) signaling plays a critical role in RILT, the molecular regulators of radiation-induced TNF-α production remain unknown. We investigated the role of a m...

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Bibliographic Details
Main Authors: Dipankar Ray, Shirish Shukla, Uday Sankar Allam, Abigail Helman, Susmita Gurjar Ramanand, Linda Tran, Michael Bassetti, Pranathi Meda Krishnamurthy, Matthew Rumschlag, Michelle Paulsen, Lei Sun, Thomas P Shanley, Mats Ljungman, Mukesh K Nyati, Ming Zhang, Theodore S Lawrence
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3585360?pdf=render

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http://europepmc.org/articles/PMC3585360?pdf=render

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