Roles of genetic polymorphisms in the folate pathway in childhood acute lymphoblastic leukemia evaluated by Bayesian relevance and effect size analysis.

Roles of genetic polymorphisms in the folate pathway in childhood acute lymphoblastic leukemia evaluated by Bayesian relevance and effect size analysis.

In this study we investigated whether polymorphisms in the folate pathway influenced the risk of childhood acute lymphoblastic leukemia (ALL) or the survival rate of the patients. For this we selected and genotyped 67 SNPs in 15 genes in the folate pathway in 543 children with ALL and 529 controls....

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Main Authors: Orsolya Lautner-Csorba, András Gézsi, Dániel J Erdélyi, Gábor Hullám, Péter Antal, Ágnes F Semsei, Nóra Kutszegi, Gábor Kovács, András Falus, Csaba Szalai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3734218?pdf=render

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http://europepmc.org/articles/PMC3734218?pdf=render

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