Development of transcriptomic resources for interrogating the biosynthesis of monoterpene indole alkaloids in medicinal plant species.

The natural diversity of plant metabolism has long been a source for human medicines. One group of plant-derived compounds, the monoterpene indole alkaloids (MIAs), includes well-documented therapeutic agents used in the treatment of cancer (vinblastine, vincristine, camptothecin), hypertension (res...

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Main Authors: Elsa Góngora-Castillo, Kevin L Childs, Greg Fedewa, John P Hamilton, David K Liscombe, Maria Magallanes-Lundback, Kranthi K Mandadi, Ezekiel Nims, Weerawat Runguphan, Brieanne Vaillancourt, Marina Varbanova-Herde, Dean Dellapenna, Thomas D McKnight, Sarah O'Connor, C Robin Buell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3530497?pdf=render