Chronic Isolation Stress Affects Central Neuroendocrine Signaling Leading to a Metabolically Active Microenvironment in a Mouse Model of Breast Cancer

Chronic Isolation Stress Affects Central Neuroendocrine Signaling Leading to a Metabolically Active Microenvironment in a Mouse Model of Breast Cancer

Social isolation is a powerful stressor capable of affecting brain plasticity and function. In the case of breast cancer, previous data indicate that stressful experiences may contribute to a worse prognosis, activating neuroendocrine and metabolism pathways, although the mechanisms underlying these...

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Bibliographic Details
Main Authors: Alessandra Berry, Barbara Collacchi, Sara Capoccia, Maria Teresa D'Urso, Serena Cecchetti, Carla Raggi, Paola Sestili, Eleonora Aricò, Giada Pontecorvi, Rossella Puglisi, Elena Ortona, Francesca Cirulli
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
social isolation stress
HPA axis
NPY/AgRP
leptin
brown adipose tissue
depression
Online Access:https://www.frontiersin.org/articles/10.3389/fnbeh.2021.660738/full

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https://www.frontiersin.org/articles/10.3389/fnbeh.2021.660738/full

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