Resveratrol Sensitizes Carfilzomib-Induced Apoptosis via Promoting Oxidative Stress in Multiple Myeloma Cells

Resveratrol Sensitizes Carfilzomib-Induced Apoptosis via Promoting Oxidative Stress in Multiple Myeloma Cells

The proteasome inhibitor is a target therapy for multiple myeloma (MM) patients, which has increased the overall survival rate of multiple myeloma in clinic. However, relapse and toxicity are major challenges for almost all MM patients. Thus, there is an urgent need for an effective and less toxic c...

Full description

Bibliographic Details
Main Authors: Qian Li, Yuanfang Yue, Lin Chen, Chang Xu, Yan Wang, Liqing Du, Xiaolei Xue, Qiang Liu, Yafei Wang, Feiyue Fan
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Pharmacology
Subjects:
resveratrol (RSV)
carfilzomib (CFZ)
proteasome
oxidative stress
autophagy
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00334/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2018.00334/full

Similar Items