Essentiality of c-di-AMP in Bacillus subtilis: Bypassing mutations converge in potassium and glutamate homeostasis.

In order to adjust to changing environmental conditions, bacteria use nucleotide second messengers to transduce external signals and translate them into a specific cellular response. Cyclic di-adenosine monophosphate (c-di-AMP) is the only known essential nucleotide second messenger. In addition to...

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Bibliographic Details
Main Authors: Larissa Krüger, Christina Herzberg, Hermann Rath, Tiago Pedreira, Till Ischebeck, Anja Poehlein, Jan Gundlach, Rolf Daniel, Uwe Völker, Ulrike Mäder, Jörg Stülke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1009092