Peptide Adjuvant to Invigorate Cytolytic Activity of NK Cells in an Obese Mouse Cancer Model

Peptide Adjuvant to Invigorate Cytolytic Activity of NK Cells in an Obese Mouse Cancer Model

Cancer patients who are overweight compared to those with normal body weight have obesity-associated alterations of natural killer (NK) cells, characterized by poor cytotoxicity, slow proliferation, and inadequate anti-cancer activity. Concomitantly, prohibitin overexpressed by cancer cells elevates...

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Bibliographic Details
Main Authors: Seungmin Han, Minjin Jung, Angela S. Kim, Daniel Y. Lee, Byung-Hyun Cha, Charles W. Putnam, Kwang Suk Lim, David A. Bull, Young-Wook Won
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Pharmaceutics
Subjects:
prohibitin binding peptide
NK cell
immunotherapy
obesity
tumor microenvironment
Online Access:https://www.mdpi.com/1999-4923/13/8/1279

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https://www.mdpi.com/1999-4923/13/8/1279

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