A New Experimental Polytrauma Model in Rats: Molecular Characterization of the Early Inflammatory Response

Background. The molecular mechanisms of the immune response after polytrauma are highly complex and far from fully understood. In this paper, we characterize a new standardized polytrauma model in rats based on the early molecular inflammatory and apoptotic response. Methods. Male Wistar rats (250 g...

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Bibliographic Details
Main Authors: Sebastian Weckbach, Mario Perl, Tim Heiland, Sonja Braumüller, Philip F. Stahel, Michael A. Flierl, Anita Ignatius, Florian Gebhard, Markus Huber-Lang
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2012/890816