The Role of High Mobility Group Box 1 in Ischemic Stroke

High-mobility group box 1 protein (HMGB1) is a novel, cytokine-like, and ubiquitous, highly conserved, nuclear protein that can be actively secreted by microglia or passively released by necrotic neurons. Ischemic stroke is a leading cause of death and disability worldwide, and the outcome is depend...

Full description

Bibliographic Details
Main Authors: Yingze Ye, Zhi Zeng, Tong Jin, Hongfei Zhang, Xiaoxing Xiong, Lijuan Gu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00127/full