Utility of ultra-sensitive qPCR to detect Plasmodium falciparum and Plasmodium vivax infections under different transmission intensities

Utility of ultra-sensitive qPCR to detect Plasmodium falciparum and Plasmodium vivax infections under different transmission intensities

Abstract Background The use of molecular diagnostics has revealed an unexpectedly large number of asymptomatic low-density malaria infections in many malaria endemic areas. This study compared the gains in parasite prevalence obtained by the use of ultra-sensitive (us)-qPCR as compared to standard q...

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Bibliographic Details
Main Authors: Maria Gruenberg, Clara Antunes Moniz, Natalie E. Hofmann, Cristian Koepfli, Leanne J. Robinson, Elma Nate, Wuelton Marcelo Monteiro, Gisely Cardoso de Melo, Andrea Kuehn, Andre M. Siqueira, Wang Nguitragool, Quique Bassat, Marcus Lacerda, Jetsumon Sattabongkot, Ivo Mueller, Ingrid Felger
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Malaria Journal
Subjects:
Ultra-sensitive
qPCR
Molecular diagnostics
Low-density
varATS
mtCOX1
Online Access:http://link.springer.com/article/10.1186/s12936-020-03374-7

Internet

http://link.springer.com/article/10.1186/s12936-020-03374-7

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