Quantitative Methods for the Detection of Tau Seeding Activity in Human Biofluids

The ability of tau aggregates to recruit and misfold monomeric tau and propagate across brain regions has been studied extensively and is now recognized as a critical pathological step in Alzheimer’s disease (AD) and other tauopathies. Recent evidence suggests that the detection of tau seeds in huma...

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Bibliographic Details
Main Authors: Aurelien Lathuiliere, Bradley T. Hyman
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Neuroscience
Subjects:
tau
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.654176/full