Genome-wide copy number profiling to detect gene amplifications in neural progenitor cells

DNA sequence amplification occurs at defined stages during normal development in amphibians and flies and seems to be restricted in humans to drug-resistant and tumor cells only. We used array-CGH to discover copy number changes including gene amplifications and deletions during differentiation of h...

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Bibliographic Details
Main Authors: U. Fischer, A. Keller, C. Backes, E. Meese
Format: Article
Language:English
Published: Elsevier 2014-12-01
Series:Genomics Data
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213596014000531