Salvianolic acid B blocks hepatic stellate cell activation via FGF19/FGFR4 signaling

Introduction and objectives: The activation of hepatic stellate cells (HSCs) is the main cause of liver fibrosis. The beneficial effects of fibroblast growth factor (FGF) 19 on liver fibrosis were recently reported. The S. miltiorrhiza as well as S. miltiorrhiza derived bioactive chemical components...

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Bibliographic Details
Main Authors: Shuxia Tian, Min Chen, Bing Wang, Yonglong Han, Haonan Shang, Junming Chen
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Annals of Hepatology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268120301745