Genome-wide capture sequencing to detect hepatitis C virus at the end of antiviral therapy

Genome-wide capture sequencing to detect hepatitis C virus at the end of antiviral therapy

Abstract Background Viral relapse is a major concern in hepatitis C virus (HCV) antiviral therapy. Currently, there are no satisfactory methods to predict viral relapse, especially in the era of direct acting antivirals in which the virus often quickly becomes undetectable using PCR-based approaches...

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Bibliographic Details
Main Authors: Peng Peng, Yanjuan Xu, Michael W. Fried, Adrian M. Di Bisceglie, Xiaofeng Fan
Format: Article
Language:English
Published: BMC 2020-08-01
Series:BMC Infectious Diseases
Subjects:
Hepatitis C virus
Multiple displacement amplification
Capture sequencing
Duplex-specific nuclease
Direct acting antivirals
Online Access:http://link.springer.com/article/10.1186/s12879-020-05355-2

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http://link.springer.com/article/10.1186/s12879-020-05355-2

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