Angiotensin-(1-7) attenuates disuse skeletal muscle atrophy in mice via its receptor, Mas

Angiotensin-(1-7) attenuates disuse skeletal muscle atrophy in mice via its receptor, Mas

Immobilization is a form of disuse characterized by a loss of strength and muscle mass. Among the main features are decreased IGF-1/Akt signalling and increased ubiquitin-proteasome pathway signalling, which induce greater myosin heavy chain degradation. Activation of the classical renin-angiotensin...

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Bibliographic Details
Main Authors: María Gabriela Morales, Johanna Abrigo, María José Acuña, Robson A. Santos, Michael Bader, Enrique Brandan, Felipe Simon, Hugo Olguin, Daniel Cabrera, Claudio Cabello-Verrugio
Format: Article
Language:English
Published: The Company of Biologists 2016-04-01
Series:Disease Models & Mechanisms
Subjects:
Disuse
Angiotensin-(1-7)
Mas receptor
Skeletal muscle
Atrophy
Online Access:http://dmm.biologists.org/content/9/4/441

Internet

http://dmm.biologists.org/content/9/4/441

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