TOX as a potential target for immunotherapy in lymphocytic malignancies
Abstract TOX (thymocyte selection-associated HMG BOX) is a member of a family of transcriptional factors that contain the highly conserved high mobility group box (HMG-box) region. Increasing studies have shown that TOX is involved in maintaining tumors and promoting T cell exhaustion. In this revie...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-03-01
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Series: | Biomarker Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s40364-021-00275-y |