Cross-talk between Aurk-A and Plk1 in mitotic entry and spindle assembly

The Aurk-A kinase is involved in different aspects of mitotic control, from mitotic entry to cytokinesis. Consistent with its pleiotropic roles, several Aurk-A interactors are able to modulate its activity, the best characterised being the microtubule binding protein TPX2, the centrosomal protein Ce...

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Bibliographic Details
Main Authors: Italia Anna Asteriti, Fabiola eDe Mattia, Giulia eGuarguaglini
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00283/full