Two dose levels of rabbit antithymocyte globulin as graft-versus-host disease prophylaxis in haploidentical stem cell transplantation: a multicenter randomized study

Two dose levels of rabbit antithymocyte globulin as graft-versus-host disease prophylaxis in haploidentical stem cell transplantation: a multicenter randomized study

Abstract Background The optimal dose of rabbit antithymocyte globulin (ATG, ImtixSangstat) minimizing infections without increasing graft-versus-host disease (GVHD) is unknown in T cell-replete, G-CSF-primed haploidentical hematopoietic stem cell transplantation (haplo-HSCT). Methods Four hundred an...

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Bibliographic Details
Main Authors: Ren Lin, Yu Wang, Fen Huang, Zhiping Fan, Shen Zhang, Ting Yang, Yajing Xu, Na Xu, Li Xuan, Jieyu Ye, Jing Sun, Xiaojun Huang, Qifa Liu
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Medicine
Subjects:
Antithymocyte globulin
Haploidentical hematopoietic stem cell transplantation
EBV
CMV
Graft-versus-host disease
Online Access:http://link.springer.com/article/10.1186/s12916-019-1393-7

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http://link.springer.com/article/10.1186/s12916-019-1393-7

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