Showing the Way: Oncolytic Adenoviruses as Chaperones of Immunostimulatory Adjuncts

Showing the Way: Oncolytic Adenoviruses as Chaperones of Immunostimulatory Adjuncts

Oncolytic adenoviruses (OAds) are increasingly recognized as vectors for immunotherapy in the treatment of various solid tumors. The myriads of advantages of using adenovirus include targeted specificity upon infection and selective replication, which lead to localized viral burst, exponential sprea...

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Bibliographic Details
Main Authors: Jing Li Huang, Christopher J. LaRocca, Masato Yamamoto
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:Biomedicines
Subjects:
oncolytic adenovirus
immunotherapy
oncolytic virotherapy
GM-CSF (granulocyte macrophage colony-stimulating factor)
interferon-α
interferon-γ
interleukin-12
CD40L
CTLA-4
Online Access:http://www.mdpi.com/2227-9059/4/3/23

Internet

http://www.mdpi.com/2227-9059/4/3/23

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