A viable hypomorphic allele of the essential IMP3 gene reveals novel protein functions in Saccharomyces cerevisiae.

In Saccharomyces cerevisiae, the essential IMP3 gene encodes a component of the SSU processome, a large ribonucleoprotein complex required for processing of small ribosomal subunit RNA precursors. Mutation of the IMP3 termination codon to a sense codon resulted in a viable mutant allele producing a...

Full description

Bibliographic Details
Main Authors: Bruno Cosnier, Marta Kwapisz, Isabelle Hatin, Olivier Namy, Sylvie Hermann-Le Denmat, Antonin Morillon, Jean-Pierre Rousset, Céline Fabret
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21559332/?tool=EBI