MALT1 Protease Activity Is Required for Innate and Adaptive Immune Responses.

MALT1 Protease Activity Is Required for Innate and Adaptive Immune Responses.

CARMA-BCL10-MALT1 signalosomes play important roles in antigen receptor signaling and other pathways. Previous studies have suggested that as part of this complex, MALT1 functions as both a scaffolding protein to activate NF-κB through recruitment of ubiquitin ligases, and as a protease to cleave an...

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Bibliographic Details
Main Authors: Jong W Yu, Sandy Hoffman, Allison M Beal, Angela Dykon, Michael A Ringenberg, Anna C Hughes, Lauren Dare, Amber D Anderson, Joshua Finger, Viera Kasparcova, David Rickard, Scott B Berger, Joshi Ramanjulu, John G Emery, Peter J Gough, John Bertin, Kevin P Foley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4428694?pdf=render

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http://europepmc.org/articles/PMC4428694?pdf=render

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