Dectin-1/Syk signaling triggers neuroinflammation after ischemic stroke in mice

Abstract Background Dendritic cell-associated C-type lectin-1 (Dectin-1) receptor has been reported to be involved in neuroinflammation in Alzheimer’s disease and traumatic brain injury. The present study was designed to investigate the role of Dectin-1 and its downstream target spleen tyrosine kina...

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Bibliographic Details
Main Authors: Xin-Chun Ye, Qi Hao, Wei-Jing Ma, Qiu-Chen Zhao, Wei-Wei Wang, Han-Han Yin, Tao Zhang, Miao Wang, Kun Zan, Xin-Xin Yang, Zuo-Hui Zhang, Hong-Juan Shi, Jie Zu, Hafiz Khuram Raza, Xue-Ling Zhang, De-Qin Geng, Jin-Xia Hu, Gui-Yun Cui
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Journal of Neuroinflammation
Subjects:
Syk
Online Access:https://doi.org/10.1186/s12974-019-1693-z