Inhibition of LPS-Induced PGE<sub>2</sub> Production by Arylsulfonamide Derivatives via the Selective Inhibition of mPGES-1 Enzyme
Microsomal prostaglandin E synthase-1 (mPGES-1) is responsible for the massive prostaglandin E<sub>2</sub> (PGE<sub>2</sub>) formation during inflammation. Increasing evidence reveals mPGES-1 inhibitors as a safe alternative to nonsteroidal anti-inflammatory drugs. Recently,...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2019-08-01
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| Series: | Proceedings |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2504-3900/22/1/37 |