A novel cell line derived from pleomorphic adenoma expresses MMP2, MMP9, TIMP1, TIMP2, and shows numeric chromosomal anomalies.

Pleomorphic adenoma is the most common salivary gland neoplasm, and it can be locally invasive, despite its slow growth. This study aimed to establish a novel cell line (AP-1) derived from a human pleomorphic adenoma sample to better understand local invasiveness of this tumor. AP-1 cell line was ch...

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Bibliographic Details
Main Authors: Aline Semblano Carreira Falcão, Maria Sueli da Silva Kataoka, Nélson Antonio Bailão Ribeiro, José Antonio Picanço Diniz, Sérgio Melo Alves, André L Ribeiro Ribeiro, Adriane Sousa de Siqueira, Artur Luiz da Silva, Rommel Thiago Jucá Ramos, Vanessa M Freitas, Ruy G Jaeger, João J V Pinheiro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4138172?pdf=render