The DEK Oncoprotein Functions in Ovarian Cancer Growth and Survival

DNA damage repair alterations play a critical role in ovarian cancer tumorigenesis. Mechanistic drivers of the DNA damage response consequently present opportunities for therapeutic targeting. The chromatin-binding DEK oncoprotein functions in DNA double-strand break repair. We therefore sought to d...

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Bibliographic Details
Main Authors: Kari E Hacker, Danielle E Bolland, Lijun Tan, Anjan K Saha, Yashar S Niknafs, David M Markovitz, Karen McLean
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558618304391