The Fast-Growing Brucella suis Biovar 5 Depends on Phosphoenolpyruvate Carboxykinase and Pyruvate Phosphate Dikinase but Not on Fbp and GlpX Fructose-1,6-Bisphosphatases or Isocitrate Lyase for Full Virulence in Laboratory Models

The Fast-Growing Brucella suis Biovar 5 Depends on Phosphoenolpyruvate Carboxykinase and Pyruvate Phosphate Dikinase but Not on Fbp and GlpX Fructose-1,6-Bisphosphatases or Isocitrate Lyase for Full Virulence in Laboratory Models

Bacteria of the genus Brucella infect a range of vertebrates causing a worldwide extended zoonosis. The best-characterized brucellae infect domestic livestock, behaving as stealthy facultative intracellular parasites. This stealthiness depends on envelope molecules with reduced pathogen-associated m...

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Bibliographic Details
Main Authors: Amaia Zúñiga-Ripa, Thibault Barbier, Leticia Lázaro-Antón, María J. de Miguel, Raquel Conde-Álvarez, Pilar M. Muñoz, Jean J. Letesson, Maite Iriarte, Ignacio Moriyón
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Microbiology
Subjects:
Brucella
metabolism
gluconeogenesis
pyruvate phosphate dikinase
phosphoenolpyruvate carboxykinase
malic enzyme
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2018.00641/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2018.00641/full

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