A biochemical mechanism for time-encoding memory formation within individual synapses of Purkinje cells.

Within the classical eye-blink conditioning, Purkinje cells within the cerebellum are known to suppress their tonic firing rates for a well defined time period in response to the conditional stimulus after training. The temporal profile of the drop in tonic firing rate, i.e., the onset and the durat...

Full description

Bibliographic Details
Main Authors: Ayush Mandwal, Javier G Orlandi, Christoph Simon, Jörn Davidsen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0251172