Mechanisms of enhanced macrophage apoE secretion by oxidized LDL

Previous studies have demonstrated that atherosclerotic lesions contain apoE synthesized primarily by macrophages. As oxidized LDL has been implicated in the development of atherosclerosis, its effect on macrophage apoE synthesis and secretion was examined. Human monocytic leukemia cells, THP-1, and...

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Bibliographic Details
Main Authors: A A Cader, F M Steinberg, T Mazzone, A Chait
Format: Article
Language:English
Published: Elsevier 1997-05-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520372229