Demonstration of a novel HIV-1 restriction phenotype from a human T cell line.

Although retroviruses may invade host cells, a productive infection can be established only after the virus counteracts inhibition from different types of host restriction factors. Fv1, APOBEC3G/F, TRIM5alpha, ZAP, and CD317 inhibit the replication of different retroviruses by interfering with viral...

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Bibliographic Details
Main Authors: Yanxing Han, Xiaojun Wang, Ying Dang, Yong-Hui Zheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2464712?pdf=render