Demonstration of a novel HIV-1 restriction phenotype from a human T cell line.
Although retroviruses may invade host cells, a productive infection can be established only after the virus counteracts inhibition from different types of host restriction factors. Fv1, APOBEC3G/F, TRIM5alpha, ZAP, and CD317 inhibit the replication of different retroviruses by interfering with viral...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-07-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2464712?pdf=render |