Epigenetic changes associated with disease progression in a mouse model of childhood allergic asthma

SUMMARY Development of asthma in childhood is linked to viral infections of the lower respiratory tract in early life, with subsequent chronic exposure to allergens. Progression to persistent asthma is associated with a Th2-biased immunological response and structural remodelling of the airways. The...

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Bibliographic Details
Main Authors: Adam Collison, Jessica S. Siegle, Nicole G. Hansbro, Chau-To Kwok, Cristan Herbert, Joerg Mattes, Megan Hitchins, Paul S. Foster, Rakesh K. Kumar
Format: Article
Language:English
Published: The Company of Biologists 2013-07-01
Series:Disease Models & Mechanisms
Online Access:http://dmm.biologists.org/content/6/4/993