Benchmarking subcellular localization and variant tolerance predictors on membrane proteins

Benchmarking subcellular localization and variant tolerance predictors on membrane proteins

Abstract Background Membrane proteins constitute up to 30% of the human proteome. These proteins have special properties because the transmembrane segments are embedded into lipid bilayer while extramembranous parts are in different environments. Membrane proteins have several functions and are invo...

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Bibliographic Details
Main Authors: Tommaso Orioli, Mauno Vihinen
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Genomics
Subjects:
Membrane protein
Benchmark
Benchmarking
Variation interpretation
Method performance
Disease-causing variant
Online Access:http://link.springer.com/article/10.1186/s12864-019-5865-0

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http://link.springer.com/article/10.1186/s12864-019-5865-0

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