Effect of Sulfonamides and Their Structurally Related Derivatives on the Activity of <i>ι</i>-Carbonic Anhydrase from <i>Burkholderia territorii</i>

Effect of Sulfonamides and Their Structurally Related Derivatives on the Activity of <i>ι</i>-Carbonic Anhydrase from <i>Burkholderia territorii</i>

Carbonic anhydrases (CAs) are essential metalloenzymes in nature, catalyzing the carbon dioxide reversible hydration into bicarbonate and proton. In humans, breathing and many other critical physiological processes depend on this enzymatic activity. The CA superfamily function and inhibition in path...

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Bibliographic Details
Main Authors: Viviana De Luca, Andrea Petreni, Alessio Nocentini, Andrea Scaloni, Claudiu T. Supuran, Clemente Capasso
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
Carbonic anhydrases
metalloenzyme
inhibitor
sulfonamides
kinetic constants
Online Access:https://www.mdpi.com/1422-0067/22/2/571

Internet

https://www.mdpi.com/1422-0067/22/2/571

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