The Combination of Mitragynine and Morphine Prevents the Development of Morphine Tolerance in Mice
Mitragynine (MG) is the major active alkaloid found in Mitragyna speciosa Korth. In the present study, we investigated the enhancement of analgesic action of MG when combined with morphine and the effect of the combination on the development of tolerance towards morphine. Mice were administered intr...
Main Authors: | Sharida Fakurazi, Shamima Abdul Rahman, Mohamad Taufik Hidayat, Hairuszah Ithnin, Mohamad Aris Mohd Moklas, Palanisamy Arulselvan |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2013-01-01
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Series: | Molecules |
Subjects: | |
Online Access: | http://www.mdpi.com/1420-3049/18/1/666 |
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