White blood cell-based detection of asymptomatic scrapie infection by ex vivo assays.

Prion transmission can occur by blood transfusion in human variant Creutzfeldt-Jakob disease and in experimental animal models, including sheep. Screening of blood and its derivatives for the presence of prions became therefore a major public health issue. As infectious titer in blood is reportedly...

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Bibliographic Details
Main Authors: Sophie Halliez, Emilie Jaumain, Alvina Huor, Jean-Yves Douet, Séverine Lugan, Hervé Cassard, Caroline Lacroux, Vincent Béringue, Olivier Andréoletti, Didier Vilette
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25122456/?tool=EBI