Crystallization and Characterization of an Inflammatory Lectin Purified from the Seeds of Dioclea wilsonii

DwL, a lectin extracted from the seeds of Dioclea wilsonii, is a metalloprotein with strong agglutinating activity against rabbit and ABO erythrocytes, inhibited by glucose and mannose. DwL was purified by affinity chromatography on a Sephadex G-50 column and ion exchange chromatography on a HiTrap...

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Main Authors: Ana Maria Sampaio Assreuy, Alana de Freitas Pires, Amanda Uliana de Carvalho, Raquel Guimarães Benevides, Rafael da Conceição Simões, Helton Colares da Silva, Maria Júlia Barbosa Bezerra, Antonia Samia Fernandes do Nascimento, Kyria Santiago do Nascimento, Celso Shiniti Nagano, Alexandre Holanda Sampaio, Plínio Delatorre, Bruno Anderson Matias da Rocha, Patricia Machado Bueno Fernandes, Benildo Sousa Cavada, Thaiz Batista Azevedo Rangel
Format: Article
Language:English
Published: MDPI AG 2011-06-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/16/6/5087/