Identification of the atypical cadherin FAT1 as a novel glypican-3 interacting protein in liver cancer cells

Identification of the atypical cadherin FAT1 as a novel glypican-3 interacting protein in liver cancer cells

Abstract Glypican-3 (GPC3) is a cell surface heparan sulfate proteoglycan that is being evaluated as an emerging therapeutic target in hepatocellular carcinoma (HCC). GPC3 has been shown to interact with several extracellular signaling molecules, including Wnt, HGF, and Hedgehog. Here, we reported a...

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Bibliographic Details
Main Authors: Panpan Meng, Yi-Fan Zhang, Wangli Zhang, Xin Chen, Tong Xu, Sheng Hu, Xinjun Liang, Mingqian Feng, Xiaoqing Yang, Mitchell Ho
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-79524-3

Internet

https://doi.org/10.1038/s41598-020-79524-3

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