ABCA1 and ABCG1 or ABCG4 act sequentially to remove cellular cholesterol and generate cholesterol-rich HDL

ABCA1 and ABCG1 or ABCG4 act sequentially to remove cellular cholesterol and generate cholesterol-rich HDL

Recent developments in lipid metabolism have shown the importance of ATP binding cassette transporters (ABCs) in controlling cellular and total body lipid homeostasis. ABCA1 mediates the transport of cholesterol and phospholipids from cells to lipid-poor apolipoprotein A-I (apoA-I), whereas ABCG1 an...

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Bibliographic Details
Main Authors: Ashley M. Vaughan, John F. Oram
Format: Article
Language:English
Published: Elsevier 2006-11-01
Series:Journal of Lipid Research
Subjects:
ATP binding cassette transporter A1
ATP binding cassette transporter G1
ATP binding cassette transporter G4
high density lipoprotein
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520433796

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http://www.sciencedirect.com/science/article/pii/S0022227520433796

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