Characterisation of peptide microarrays for studying antibody-antigen binding using surface plasmon resonance imagery.

BACKGROUND: Non-specific binding to biosensor surfaces is a major obstacle to quantitative analysis of selective retention of analytes at immobilized target molecules. Although a range of chemical antifouling monolayers has been developed to address this problem, many macromolecular interactions sti...

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Bibliographic Details
Main Authors: Claude Nogues, Hervé Leh, Christopher G Langendorf, Ruby H P Law, Ashley M Buckle, Malcolm Buckle
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2921342?pdf=render