Characterizing responsive and refractory orthotopic mouse models of hepatocellular carcinoma in cancer immunotherapy.

Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide and has a high mortality rate due to limited treatment options. Hence, the response of HCC to different cancer immunotherapies is being intensively investigated in clinical trials. Immune checkpoint blockers (ICB) show promis...

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Bibliographic Details
Main Authors: Carina Hage, Sabine Hoves, Mailin Ashoff, Veronika Schandl, Stefan Hört, Natascha Rieder, Christian Heichinger, Marco Berrera, Carola H Ries, Fabian Kiessling, Thomas Pöschinger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0219517