Resveratrol downregulates TGF-β1 and Smad3 expression and attenuates oxidative stress in CCl4-induced kidney damage in rats

Resveratrol downregulates TGF-β1 and Smad3 expression and attenuates oxidative stress in CCl4-induced kidney damage in rats

Objective: To evaluate the effect of resveratrol against CCl4- induced nephrotoxicity. Methods: Forty-two male Wistar rats were divided into seven groups randomly. After six weeks, kidney weight, body weight, blood urea, serum creatinine, oxidative stress markers, and gene expression of renal transf...

Full description

Bibliographic Details
Main Authors: Saeed Mohammadi, Jamshid Karimi, Heidar Tavilani, Iraj Khodadadi, Roohollah Mohseni, Mohammad Hashemnia
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
nephrotoxicity; transforming growth factor beta1; resveratrol; carbon tetrachloride
Online Access:http://www.apjtb.org/article.asp?issn=2221-1691;year=2020;volume=10;issue=9;spage=397;epage=402;aulast=Mohammadi

Internet

http://www.apjtb.org/article.asp?issn=2221-1691;year=2020;volume=10;issue=9;spage=397;epage=402;aulast=Mohammadi

Similar Items