Gli2a protein localization reveals a role for Iguana/DZIP1 in primary ciliogenesis and a dependence of Hedgehog signal transduction on primary cilia in the zebrafish

Gli2a protein localization reveals a role for Iguana/DZIP1 in primary ciliogenesis and a dependence of Hedgehog signal transduction on primary cilia in the zebrafish

<p>Abstract</p> <p>Background</p> <p>In mammalian cells, the integrity of the primary cilium is critical for proper regulation of the Hedgehog (Hh) signal transduction pathway. Whether or not this dependence on the primary cilium is a universal feature of vertebrate Hed...

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Bibliographic Details
Main Authors: van Eeden Freek, Richardson Joanna, Kim Hyejeong, Ingham Philip W
Format: Article
Language:English
Published: BMC 2010-04-01
Series:BMC Biology
Online Access:http://www.biomedcentral.com/1741-7007/8/65

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http://www.biomedcentral.com/1741-7007/8/65

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